HYPERSPLENISM

Hypersplenism in cirrhosis.

Hypersplenism: History and current status

Hypersplenism is a common disorder characterized by an enlarged spleen which causes rapid and premature destruction of blood cells. This review summarizes the history of hypersplenism, discuss its classification and pathogenesis, and examines its diagnosis and treatment options. We performed a comprehensive literature search using PubMed, Web of Knowledge and the China National Knowledge Infras...

Splenomegaly, hypersplenism, and hereditary disorders with splenomegaly

Splenomegaly, sometimes of massive extent, occurs in a large number of hereditary diseases, some relatively prevalent and others, rare to ultra-rare. Because physicians are often unfamiliar with the less common disorders, patients may suffer because of diagnostic delay or diagnostic error and may undergo invasive, non-innocuous procedures such as splenectomy that are potentially avoidable were ...

Humoral factor (s) in experimental hypersplenism.

I HE SYNDROME of hypersplenism is characterized by splenomegaly, selective or total blood cytopenias, normal or hyperplastic bone marrow, and disappearance of the cytopenias after splenectomy. The mechanism of the various forms of hypersplenism ( splenic thrombocytopenia, spenic anemia, splenic neutropenia, splenic pancytopenia ) is still under discussion. Clinical and experimental evidence has...

Hypersplenism; a case report with postmortem study.